Next Issue
Volume 4, March
Previous Issue
Volume 3, September
 
 

Mar. Drugs, Volume 3, Issue 4 (December 2005) – 3 articles , Pages 113-126

  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list.
  • You may sign up for e-mail alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.
Order results
Result details
Section
Select all
Export citation of selected articles as:
13 KiB  
Editorial
Farewell Address of Marine Drugs Executive Editor-in-Chief
by Peter Proksch
Mar. Drugs 2005, 3(4), 126; https://doi.org/10.3390/md304126 - 22 Dec 2005
Viewed by 5168
Abstract
After serving as the Executive Editor-in-Chief for Marine Drugs for almost three years I am now stepping back from this position but will remain attached to the Journal by serving on the Editorial Board.[...] Full article
70 KiB  
Article
Effects of Polybrominated Diphenol Ethers from a Marine Sponge Phyllospongia dendyi on IL-8 Production in a PMAstimulated Promyelocytic Leukemia Cell Line
by Taiko Oda, Hongwei Liu and Michio Namikoshi
Mar. Drugs 2005, 3(4), 119-125; https://doi.org/10.3390/md304119 - 03 Nov 2005
Cited by 10 | Viewed by 8778
Abstract
The effects of five polybrominated diphenol ethers from a Marine Sponge, Phyllospongia dendyi, on the relative plating efficiencies in V79 cells and the cell proliferation and IL-8 production in PMA-stimulated HL-60 cells were examined. Three compounds, possessing two phenol units, were reported to [...] Read more.
The effects of five polybrominated diphenol ethers from a Marine Sponge, Phyllospongia dendyi, on the relative plating efficiencies in V79 cells and the cell proliferation and IL-8 production in PMA-stimulated HL-60 cells were examined. Three compounds, possessing two phenol units, were reported to inhibit the assembly of microtubule proteins and showed the inhibition of colony formation of V79 cells and increase in IL-8 production. Interestingly, a monomethoxy compound exhibited the stronger activity than the three active compounds in both bioassays. This compound did not inhibit the assembly of microtubule proteins. A dimethoxy compound was not active in either bioassays. In these experimental conditions, the biological activities were not high, but in future, these compounds will be expected to be made stronger by structural modifications. Full article
Show Figures

50 KiB  
Article
Luteophanol D, New Polyhydroxyl Metabolite from Marine Dinoflagellate Amphidinium sp.
by Takaaki Kubota, Ayako Takahashi, Masashi Tsuda and Jun\'ichi Kobayashi
Mar. Drugs 2005, 3(4), 113-118; https://doi.org/10.3390/md304113 - 02 Nov 2005
Cited by 46 | Viewed by 7915
Abstract
Luteophanol D (1), a new polyhydroxyl linear carbon-chain metabolite, has been isolated from the cultured marine dinoflagellate Amphidinium sp., which was isolated from Okinawan marine acoel flatworm Pseudaphanostoma luteocoloris. The structure of 1 was elucidated by detailed analyses of 2D NMR spectra. Luteophanol [...] Read more.
Luteophanol D (1), a new polyhydroxyl linear carbon-chain metabolite, has been isolated from the cultured marine dinoflagellate Amphidinium sp., which was isolated from Okinawan marine acoel flatworm Pseudaphanostoma luteocoloris. The structure of 1 was elucidated by detailed analyses of 2D NMR spectra. Luteophanol D (1) possesses two tetrahydropyran rings and twenty-three hydroxyl groups on C63-linear aliphatic chain with one exo-methylene and two methyl branches. Full article
Show Figures

Previous Issue
Next Issue
Back to TopTop