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Mar. Drugs, Volume 3, Issue 3 (September 2005) – 3 articles , Pages 78-112

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Editorial
Withdrawn Paper: Rajeev Kumar Jha * and Xu Zi-Rong. Review: Biomedical Compounds from Marine Organisms, Marine Drugs 2004, 2, 123-146
by Peter Proksch, Derek J. McPhee and Shu-Kun Lin
Mar. Drugs 2005, 3(3), 112; https://doi.org/10.3390/md303112 - 27 Oct 2005
Cited by 1 | Viewed by 8485
Abstract
It has been brought to our attention by a member of our Editorial Board that substantial portions of this review article have been copied verbatim from earlier publications without credit.[...] Full article
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Article
Polycitorols A and B, New Tricyclic Alkaloids from an Ascidian
by Hamad H. Issa, Junichi Tanaka, Rachmaniar Rachmat, Andi Setiawan, Agus Trianto and Tatsuo Higa
Mar. Drugs 2005, 3(3), 78-83; https://doi.org/10.3390/md303078 - 23 Sep 2005
Cited by 19 | Viewed by 9330
Abstract
Two new tricyclic alkaloids, polycitorols A (1) and B (2) have been isolated along with the known lepadiformine (3) from a marine ascidian of the family Polycitoridae. The structures of the new compounds were elucidated by analysis of NMR data and comparison with [...] Read more.
Two new tricyclic alkaloids, polycitorols A (1) and B (2) have been isolated along with the known lepadiformine (3) from a marine ascidian of the family Polycitoridae. The structures of the new compounds were elucidated by analysis of NMR data and comparison with those of 3 and other related compounds [1-5]. Compounds 1 and 2 are closely related to cylindricines A and B, lacking C-4 oxygenation found in cylindricines and having a butyl instead of a hexyl appendage. NOE experiments on compounds 1 and 2 suggested the A/B ring fusion to be cis. Full article
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Review
Sterol Ring System Oxidation Pattern in Marine Sponges
by Nittala S. Sarma, M. Sri Rama Krishna and S. Ramakrishna Rao
Mar. Drugs 2005, 3(3), 84-111; https://doi.org/10.3390/md303084 - 07 Jun 2005
Cited by 40 | Viewed by 11253
Abstract
The marine sponges (Porifera) are a unique group of sedentary organisms from which several novel natural products are reported, many of which have useful biological activities. In producing unusual sterols, they occupy a preeminent position among the various groups of organisms. The polar [...] Read more.
The marine sponges (Porifera) are a unique group of sedentary organisms from which several novel natural products are reported, many of which have useful biological activities. In producing unusual sterols, they occupy a preeminent position among the various groups of organisms. The polar sterols of sponges reported as at the end of the year 2002 number about 250; their ring structure changing a hundred times. The oxidation pattern in the sterol ring system, from the point of view of biogenesis seems to be mainly of four types. Each sponge species is able to produce sterols fitting into one of the four main biogenetic pathways viz., (i) 3β-hydroxy-Δ5-sterol pathway, (ii) 3β-hydroxy-Δ7-sterol pathway, (iii) 3β-hydroxy-Δ5,7-sterol pathway, and (iv) 3α-hydroxy sterol pathway. Full article
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