Molecules

101 KiB

Open AccessArticle

Applications of Microwave in Organic Synthesis: An Improved One-step Synthesis of Metallophthalocyanines and a New Modified Microwave Oven for Dry Reactions

by Didier Villemin, Mohamed Hammadi, Messaoud Hachemi and Nathalie Bar

Molecules 2001, 6(10), 831-844; https://doi.org/10.3390/61000831 - 31 Oct 2001

Cited by 47 | Viewed by 15281

Abstract

Metallophthalocyanine complexes are obtained quickly and efficiently by the reaction of phthalodinitrile with hydrated metallic salts without solvent and under microwave irradiation. The use of a modified commercial microwave oven to perform this type of reactions under dry conditions is described. Metallophthalocyanines and metallododecachlorophthalocyanines of some divalent metals can be also obtained from phthalic or tetrachlorophthalic anhydrides with hydrated metallic salt and urea under microwave irradiation and without solvent. Full article

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30 KiB

Open AccessArticle

A Convenient Method to Prepare Labile FMN Derivatives

by Franz Müller and John Lee

Molecules 2001, 6(10), 825-830; https://doi.org/10.3390/61000825 - 31 Oct 2001

Cited by 1 | Viewed by 6524

Abstract

A simple method for selective phosphorylation of ribityl containing starting materials to afford FMN derivatives is presented. The method is in particular valuable for the synthesis of labile FMN derivatives. Full article

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93 KiB

Open AccessArticle

Synthesis, Antibacterial and Antifungal Activity of 4-Substituted-5-Aryl-1,2,4-Triazoles

by Katica Colanceska-Ragenovic, Vesna Dimova, Vlado Kakurinov, Dora Gabor Molnar and Aleksandra Buzarovska

Molecules 2001, 6(10), 815-824; https://doi.org/10.3390/61000815 - 30 Sep 2001

Cited by 135 | Viewed by 9633

Abstract

A few 4-allyl/amino-5-aryl-1,2,4-triazoles were synthesized and tested for antibacterial and antifungal effects against Escherichia coli, Bacillus subtilis, Salmonella enteritidis, Staphylococcus aureus, Aspergillus niger and Candida albicans. 4-Allyl-5-aryl-1,2,4-triazoles were obtained by the oxidative cyclization of the appropriate 1-substituted-4-allylthiosemicarbazides and 4-amino-5-aryl-1,2,4-triazoles were obtained by cyclization of the potassium salts of appropriately substituted dithiocarbazinic acids with hydrazine hydrate. The new synthesized compounds were characterized using IR, ¹H- NMR, ¹³C-NMR and UV spectral data together with elemental analysis. Full article

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110 KiB

Open AccessArticle

Synthesis of the Aspidosperma Alkaloid Na-Formyl-16-α-Hydroxyaspidospermidine

by Fatiha Belferdi and Abdelhamid Belattar

Molecules 2001, 6(10), 803-814; https://doi.org/10.3390/61000803 - 30 Sep 2001

Viewed by 6712

Abstract

The first total synthesis of N_a-formyl-16α-hydroxyaspidospermidine and its isomer via (±)-vincadifformine is described and their structure elucidation using different methods of analysis is reported. Full article

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38 KiB

Open AccessArticle

Unambiguous Assignment of the ¹H- and ¹³C-NMR Spectra of Propafenone and a Thiophene Analogue

by Wolfgang Holzer

Molecules 2001, 6(10), 796-802; https://doi.org/10.3390/61000796 - 30 Sep 2001

Cited by 5 | Viewed by 8948

Abstract

Full and unambiguous asssignment of all ¹H- and ¹³C-NMR resonances of the free bases as well as the hydrochloride salts of the antiarrhythmic agent propafenone and a thiophene analogue in different solutions (DMSO-d₆, CDCl₃) is reported. Full article

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Molecules, Volume 6, Issue 10 (October 2001) – 5 articles , Pages 796-844

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