Next Issue
Volume 5, June
Previous Issue
Volume 5, April
 
 
molecules-logo

Journal Browser

Journal Browser

Molecules, Volume 5, Issue 5 (May 2000) – 8 articles , Pages 701-755

  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list.
  • You may sign up for e-mail alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.
Order results
Result details
Section
Select all
Export citation of selected articles as:
5 KiB  
Book Review
Agrochemicals: Composition, Production, Toxicology, Applications. Edited by Franz Müller
by Shu-Kun Lin
Molecules 2000, 5(5), 712-713; https://doi.org/10.3390/50500712 - 25 May 2000
Viewed by 4895
Abstract
This book is a valuable source of information for those involved in modern agricultural practices.[...] Full article
262 KiB  
Article
Behaviour of Some Activated Nitriles Toward Barbituric Acid, Thiobarbituric Acid and 3-Methyl-1-Phenylpyrazol-5-one
by H. M.F. Madkour, M. R. Mahmoud, M. H. Nassar and M. M. Habashy
Molecules 2000, 5(5), 746-755; https://doi.org/10.3390/50500746 - 20 May 2000
Cited by 11 | Viewed by 7842
Abstract
The effect of some active methylene containing heterocyclic compounds, namely barbituric acid, thiobarbituric acid and 3-methyl-1-phenylpyrazol-5-one on a-cyano-3,4,5-trimethoxycinnamonitrile and ethyl a-cyano-3,4,5-trimethoxycinnamate (1a,b) was investigated. The structure of the new products was substantiated by their IR,1H-NMR and mass spectra. Full article
Show Figures

Figure 1

35 KiB  
Article
Structural Elucidation of Z- and E- Isomers of 5-Alkyl-4-ethoxycarbonyl-5-(4`-chlorophenyl)-3-oxa-4-pentenoic Acids
by H. M. F. Madkour
Molecules 2000, 5(5), 737-745; https://doi.org/10.3390/50500737 - 20 May 2000
Cited by 2 | Viewed by 7582
Abstract
Z- and E-isomers of 5-alkyl-4-ethoxycarbonyl-5-(4`-chlorophenyl)-3-oxa-4-pentenoic acids were prepared via the condensation of p-chloroacetophenone and/or pchloropropiophenone with diethyl-2,2`-oxydiacetate in the presence of sodium hydride as a basic catalyst. The Z-isomers of 2a and 2b were found to be predominant. The behaviour of the corresponding [...] Read more.
Z- and E-isomers of 5-alkyl-4-ethoxycarbonyl-5-(4`-chlorophenyl)-3-oxa-4-pentenoic acids were prepared via the condensation of p-chloroacetophenone and/or pchloropropiophenone with diethyl-2,2`-oxydiacetate in the presence of sodium hydride as a basic catalyst. The Z-isomers of 2a and 2b were found to be predominant. The behaviour of the corresponding anhydrides towards the action of hydrazine, phenylhydrazine, primary aromatic amines, hydrocarbons and ethanolysis has also been investigated. The structures and configurations of the products have been elucidated by chemical and spectroscopic means. Full article
Show Figures

Figure 1

17 KiB  
Article
Synthesis of 2’-Modified Nucleotides
by Mariana Gallo, Héctor Torres and Adolfo Iribarren
Molecules 2000, 5(5), 727-729; https://doi.org/10.3390/50500727 - 15 May 2000
Viewed by 6241
Abstract
We show in this work the development of modified building blocks for the synthesis of nuclease resistant hammerhead ribozymes. These modified monomers retain the 2’-OH which is essential for the activity of these molecules. Our final goal is to generate a catalytic antisense [...] Read more.
We show in this work the development of modified building blocks for the synthesis of nuclease resistant hammerhead ribozymes. These modified monomers retain the 2’-OH which is essential for the activity of these molecules. Our final goal is to generate a catalytic antisense approach with potential application in gene therapy. Full article
42 KiB  
Article
Synthesis of N,N’-Diarylalkanediamides and Their Antimycobacterial and Antialgal Activity
by Lenka Kubicova, Karel Waisser, Jiri Kunes, Katarina Kralova, Zelmira Odlerova, Milan Slosarek, Jiri Janota and Zbynek Svoboda
Molecules 2000, 5(5), 714-726; https://doi.org/10.3390/50500714 - 14 May 2000
Cited by 17 | Viewed by 9229
Abstract
A set of N,N'-diarylalkanediamides was synthesized. The compounds were tested for their antimycobacterial and antialgal activity. The antimycobacterial activity of N,N'-diarylalkanediamides depends on the lipophilicity of the respective acid. Antimycobacterially active substances were found only in the series of N,N'-diarylethanediamides and N,N'-diarylbutanediamides. Other [...] Read more.
A set of N,N'-diarylalkanediamides was synthesized. The compounds were tested for their antimycobacterial and antialgal activity. The antimycobacterial activity of N,N'-diarylalkanediamides depends on the lipophilicity of the respective acid. Antimycobacterially active substances were found only in the series of N,N'-diarylethanediamides and N,N'-diarylbutanediamides. Other compounds (derivatives of pentane-, hexane-, octane- and nonanediamide) were inactive against various strains of mycobacteria. The compounds inhibited growth and chlorophyll production in Chlorella vulgaris. Their relatively low antialgal activity is probably connected with their lowered aqueous solubility, and hence by a restricted passage of the inhibitor through the hydrophilic regions of thylakoid membranes. Full article
Show Figures

Scheme 1

42 KiB  
Article
Utility of Sulphones in Heterocyclic Synthesis: Synthesis of Some Pyridine, Chromene and Thiophene Derivatives
by A. A. Fadda, Hala M. Refat and M. E. A. Zaki
Molecules 2000, 5(5), 701-709; https://doi.org/10.3390/50500701 - 5 May 2000
Cited by 21 | Viewed by 8147
Abstract
Phenylsulfonylacetonitrile (1) when reacted with α,β-unsaturated nitriles (2a,b) and/or 2-hydroxynaphthaldehyde yields pyridine derivatives (3a,b) and / or the iminochromene derivative (4) respectively. The behavior of (1) towards some a-halogenated compounds has been investigated. Full article
Show Figures

Scheme 1

5 KiB  
Book Review
The Age of the Molecule. Edited by Nina Hall
by Shu-Kun Lin
Molecules 2000, 5(5), 710-711; https://doi.org/10.3390/50500710 - 23 Apr 2000
Viewed by 4600
Abstract
It is the age of the Internet, or the age of information.[...] Full article
38 KiB  
Article
Synthesis and Characterization of New Surface Active Azo Initiators for Radical Reactions
by Milos Sedlak and Klaus Tauer
Molecules 2000, 5(5), 730-736; https://doi.org/10.3390/50500730 - 18 Apr 2000
Cited by 12 | Viewed by 8773
Abstract
The synthesis of a water soluble azo initiators from 2,2’-azodiisobutyronitrile (AIBN) was performed in three steps: reaction of dinitrile with aromatic alcohols in the presence of HCl to form bisiminoesters hydrochlorides which are hydrolyzed to the esters and final regioselective sulfonation of the [...] Read more.
The synthesis of a water soluble azo initiators from 2,2’-azodiisobutyronitrile (AIBN) was performed in three steps: reaction of dinitrile with aromatic alcohols in the presence of HCl to form bisiminoesters hydrochlorides which are hydrolyzed to the esters and final regioselective sulfonation of the aromatic esters. The thermal decomposition of the azo initiators obtained leads to formation of two surface active radicals which can start the chain reaction. Full article
Show Figures

Figure 1

Previous Issue
Next Issue
Back to TopTop